| 引用本文： |
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赵红梅,张洁,杨小青,等.上海市陆家嘴地区公司职员非酒精性脂肪肝发病率及危险因素分析[J].同济大学学报（医学版）,2012,33(5):110-114. [点击复制]
- ZHAO Hong-mei,ZHANG Jie,YANG Xiao-qing,et al.Prevalence of non-alcoholic fatty liver disease in office workers of Shanghai Lujiazui District and its risk factors[J].同济大学学报（医学版）,2012,33(5):110-114. [点击复制]
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| 摘要: |
| 目的明确上海市陆家嘴地区公司职员非酒精性脂肪肝(non-alcoholic fatty liver disease,NAFLD)的发病率及相关危险因素。方法选取从2008年1月到2011年8月来同济大学附属东方医院体检的上海市陆家嘴地区公司在职职员,进行血液及肝脏超声检查。结果共3 532人完成调查,其中男性1 709人,平均年龄(41.99±9.04)岁,共检出NAFLD患者1 265例,患病率为35.8%,其中男性患病率为53.5%,女性为19.1%,男女性患病率均在41～50岁年龄组达到高峰(分别为61.3%和27.4%),在各个年龄组中男性患病率均高于女性(P<0.01)。Logistic回归分析发现年龄、体质量、血尿酸、血HDL-C及ALT与NAFLD独立相关。结论陆家嘴地区公司在职职员中NAFLD发病率高,与年龄、体质量、血尿酸、HDL-C及ALT水平相关。 |
| 关键词: 非酒精性脂肪肝 患病率 危险因素 |
| DOI：10.3969/j.issn1008 -0392.2012.05.026 |
| 投稿时间：2012-01-13 |
| 基金项目: |
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| Prevalence of non-alcoholic fatty liver disease in office workers of Shanghai Lujiazui District and its risk factors |
| ZHAO Hong-mei,ZHANG Jie,YANG Xiao-qing,ZHOU Jie-ru,HAN Jie |
| (Dept.of VIP Clinic,East Hospital,Tongji University,Shanghai 200120,China) |
| Abstract: |
| Objective To determine the prevalence and risk factors of non-alcoholic fatty liver disease (NAFLD) among office workers of Shanghai Lujiazui District. Methods Total 3 532 office workers with a mean age of 41. 9 y, including 1709 men and 1823 women from Lujiazui District underwent health check-up in our hospital from August 2008 to August 2011. The results of physical examination, blood tests and sonography examination were analyzed. Results NAFLD was found in 1 265 (35. 8%) subjects, with a prevalence rate of 53.5% in males and 19. 1% in females. The prevalence of NAFLD in 41 -50 age group was highest in both sex (61. 3% and 27. 4% for male and female respectively). Multivariate logistic regression analysis showed that age, body weight, blood uric acid, HDL-C and ALT levels were closely related to NAFLD. Conclusion NAFLD is a common finding in office workers of Shanghai Lujiazui District； age, weight, uric acid, HDL-C and ALT are risk factors for NAFLD. |
| Key words: non~alcoholic fatty liver disease epidemiology risk factor |
