| 摘要: |
| 静脉血栓栓塞症是一种常见且易复发的疾病。在停止抗凝治疗后血栓复发的风险与继续抗凝而致出血的风险之间如何取得平衡是临床医生面临的难题。近年来许多复发性静脉血栓形成的危险因素已经确定，然而预测个别患者血栓的复发仍然是一个挑战。本文通过综述国内外建立的复发性静脉血栓预测模型，包括Vienna模型、HERDOO2模型、DASH评分、DAMOVES评分、L-TRRiP预测模型及两种基因预测模型——5-SNP GRS和8-SNP GRS，分析各模型在预测静脉血栓复发中的优缺点，以便更好地预测静脉血栓的复发，指导患者抗凝剂的正确使用。 |
| 关键词: 静脉血栓 复发 风险 风险预测模型 无诱因的 |
| DOI：10.16118/j.1008-0392.2020.03.024 |
| 投稿时间：2019-07-10 |
| 基金项目:上海市科学技术委员会中医引导项目（19401930700）；上海市卫健委急诊与危重症重要薄弱学科项目（2016ZB0204） |
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| Research progress of risk assessment model for unprovoked recurrent venous thromboembolism |
| WANG Meng-meng,SONG Yan-li |
| (Dept. of Emergency, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China) |
| Abstract: |
| Venous thromboembolism（VTE) is a common disease and it is liable to relapse. Striking a balance between the risk of recurrent thrombosis after discontinuation of anticoagulant therapy and the risk of bleeding due to anticoagulant therapy is hard for clinicians. In recent years, many risk factors for recurrent VTE have been identified. However, it is still a challenge to predict the recurrence of VTE in individual patients. This review aims to better predict the recurrence of VTE and guide the use of anticoagulants by analyzing the advantages and disavantages of established models for recurrent VTE which include Vienna model, HERDOO2 model, the DASH score, DAMOVES score, L-TRRiP model and two kinds of gene prediction model 5-SNP GRS and 8-SNP GRS. |
| Key words: venous thrombosis recurrence risk risk assessment model unprovoked |
