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于淼,彭艾,余晨,等.2型糖尿病肾病患者生存质量多重线性逐步回归分析[J].同济大学学报（医学版）,2017,38(5):108-112. [点击复制]
YU Miao,PENG Ai,YU Chen,et al.Factors influencing the health-related quality of life in patients with type 2 diabetic kidney disease[J].同济大学学报（医学版）,2017,38(5):108-112. [点击复制]

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2型糖尿病肾病患者生存质量多重线性逐步回归分析
于淼,彭艾,余晨,艾自胜
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(同济大学医学院统计学教研室，上海200092;同济大学附属第十人民医院肾脏风湿科;上海20007;同济大学附属同济医院肾脏内科;上海200065)

摘要:

目的了解2型糖尿病肾病住院患者生存质量的现状，分析其相关因素，为控制疾病和提高患者生存质量提供理论依据。方法采用世界卫生组织生存质量测定简表(WHOQOL-BREF)调查2015年6月至2016年4月173例2型糖尿病肾病患者的生存质量情况，利用SPSS 20.0进行单因素分析、Spearman相关分析、多重线性逐步回归分析2型糖尿病肾病患者生存质量影响因素。结果单因素分析发现与2型糖尿病肾病患者生存质量相关的因素有：糖尿病病程（P＜0.05）、高血压（P＜0.05）、血糖监测频率（P＜0.05）及体育锻炼频率（P＜0.05），多重线性逐步回归分析发现高血压（β=-4.719, 95%CI： -8.944～-0.493， P=0.029）及体育锻炼频率（β=2.068, 95%CI： 0.176～3.961， P=0.032）是2型糖尿病肾病患者生存质量的重要影响因素。结论高血压及体育锻炼频率是2型糖尿病肾病患者生存质量的重要影响因素，患者应进行体育锻炼并及时监测血压以提高自身生存质量。

关键词: 2型糖尿病肾病生存质量影响因素

DOI：10.16118/j.1008-0392.2017.05.022

投稿时间：2017-02-27

基金项目:

Factors influencing the health-related quality of life in patients with type 2 diabetic kidney disease

YU Miao,PENG Ai,YU Chen,AI Zi-sheng

(Dept. of Medical Statistics, School of Medicine, Tongji University, Shanghai 200092, China;Dept. of Nephrology, Tenth Peoples Hospital, Tongji University, Shanghai 200072, China;Dept. of Nephrology, Tongji Hospital, Tongji University, Shanghai 200065, China)

Abstract:

Objective To evaluate the health-related quality of life(HQL) in patients with type 2 diabetic kidney disease (DKD), and its influencing factors. MethodsThe HQL was evaluated with WHOQOL-BREF in 173 patients between June 2015 and April 2016. The correlation of quality of life with various factors was assessed with Spearman correlation analysis and multivariate regression analysis using SPSS version 20.0. ResultsHypertension （β=-4.719, 95%CI： -8.944--0.493， P=0.029） and the frequency of exercise （β=2.068, 95%CI： 0.1763.961， P=0.032）were associated with HQL in DKD patients. ConclusionHypertension and physical exercise frequency are important factors of the quality of life in patients with DKD. The patients should do physical exercise and monitor blood pressure to improve their quality of life.

Key words: type 2 diabetic kidney disease health-related quality of life influencing factor