ZENG Zeng,ZHANG Shu-pin,WU Rong,et al.Breast imaging reporting and data system(BI-RADS) and virtual touch tissue imaging quantification(VTIQ) in diagnosis minimal breast carcinoma[J].同济大学学报（医学版）,2016,37(6):12-17. [点击复制]
(Dept.of Medical Ultrasonography, Tenth People's Hospital, Tongji University, Shanghai 200072, China;Ultrasound Research and Education Institute, Tongji University, Shanghai 200072, China;Zhejiang Provincial People's Hospital, Zhejiang Hangzhou 310000, China)
Abstract:
Objective To evaluate breast imaging reporting and data system(BI-RADS), virtual touch tissue imaging quantification(VTIQ) and combined application of the two methods in diagnosis of minimal breast carcinoma(MBC). Methods Clinical and imaging data of 94 female patients with 96 pathologically confirmed MBC admitted from June 2014 to July 2015 were retrospective analysis. Using the pathology results as the gold standard, the diagnostic value of BI-RADS, VTIQ and combination of two methods were evaluated, in terms of sensitivity, specificity, positive predictive value(PPV), negative predictive value(NPV) and diagnostic correct rate. The receiver operating characteristic(ROC) analysis was performed and the area under the curve(AUC) was calculated. Results Among 96 MBC lesions, 72(75%)were diagnosed as malignant and 24(25%)were as benign by pathology. As diagnosed by BI-RADS, 26 lesions were malignant and 70 were benign with a diagnostic sensitivity of 70.83%, specificity of 87.5%, PPV of 65.3%, NPV of 90.0% and the correct rate of 83.33%; as diagnosed by VTIQ, 27 lesions were malignant lesions and 69 were benign with a diagnostic sensitivity of 79.16%, specificity of 88.89%, PPV of 70.37%, NPV of 92.75% and the correct rate of 86.45%; as diagnosed by combination of two methods, 36 lesions were malignant and 60 were benign with a diagnostic sensitivity of 91.67%, specificity of 80.56%, PPV of 61.11%, NPV of 96.67% and the correct rate of 83.33%. The AUC of the three diagnostic methods were 0.785,0.840 and 0.861, respectively. Conclusion The combined application of VTIQ and BI-RADS is an effective supplementary to conventional images in diagnosis of minimal breast carcinoma.
