| 摘要: |
| 角膜新生血管(corneal neovascularization,CNV)可能是角膜对各种刺激的生理性反应,也可发展成病理性新生血管,是潜在的致盲因素。本综述简要回顾角膜新生血管的危险因素和发病机制,重点对新生血管的治疗进行综述。在内科治疗方面,概述了激素、非甾体抗炎药、血管内皮生长因子抑制剂、环孢霉素、维生素C、细胞凋亡诱导因子、纤维蛋白溶酶原、过氧化物酶-6和基因治疗。在外科治疗方面,概述了激光治疗、光动力治疗、浅表角膜切除术和细针透热疗法。 |
| 关键词: 角膜新生血管 治疗 药物 |
| DOI：10.3969/j.issn1008-0392.2013.03.034 |
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| 基金项目:国家自然科学基金（30973247） |
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| Advances in treatment of corneal neovascularization |
| TANG Shen-fei,BI Yan-long |
| (Dept.of Ophthalmology,Tongji Hospital,Tongji University,Shanghai 200065,China) |
| Abstract: |
| Corneal neovascularization（CNV） is a physiological response to various stimuli,and may develop into pathological CNV.In this article we review the risk factors and pathogenesis of CNV,and focus on the treatment.The medical treatment of CNV includes steroids,nonsteroidal anti-inflammatory drugs,vascular endothelial growth factor inhibitor,cyclosporine,vitamin C,apoptosis inducing factor,plasminogen,peroxiredoxin-6 and gene therapy.The surgical treatment includes laser therapy,photodynamic therapy,superficial keratectomy,and fine-needle diathermy. |
| Key words: corneal neovascularization treatment medicine |
