| 引用本文： |
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潘涛,林福清,李泉,等.加巴喷丁联合神经阻滞治疗带状疱疹后神经痛[J].同济大学学报（医学版）,2011,32(1):86-88. [点击复制]
- PAN Tao,LIN Fu-qing,LI Quan,et al.Gabapendin combined with nerve block for the treatment of patients with post-herpetic neuralgia[J].同济大学学报（医学版）,2011,32(1):86-88. [点击复制]
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| 摘要: |
| 目的 采用加巴喷丁联合神经阻滞治疗带状疱疹后神经痛,观察其有效性和安全性。方法 将60例PHN患者随机分为2组,每组30例,分别接受神经阻滞（A组）和口服加巴喷丁联合神经阻滞治疗（B组）,共治疗6周。用视觉模拟评分（visual analogue scale,VAS）和24 h睡眠时间来评价治疗效果,同时观察并发症及药物不良反应。结果 在6周观察期间,两组患者治疗后各时点与治疗前相比疼痛评分随时间下降,睡眠时间均增加（P＜0.05）。B组的VAS评分下降大于A组,24 h睡眠时间增加大于A组（P＜0.05）。两组未出现并发症及严重的药物副作用。结论 加巴喷丁联合神经支阻滞治疗带状疱疹后神经痛,可迅速缓解疼痛,改善睡眠质量,疗效确切,效果优于单独神经阻滞,且无明显不良反应。 |
| 关键词: 加巴喷丁 带状疱疹后神经痛 神经阻滞 |
| DOI：10.3969/j.issn1008-0392.2011.01.086 |
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| 基金项目: |
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| Gabapendin combined with nerve block for the treatment of patients with post-herpetic neuralgia |
| PAN Tao,LIN Fu-qing,LI Quan,FU Shu-kun,JI Xuan |
| (Dept.of Anesthesiology,Tenth People's Hospital,Tongji University,Shanghai 200072,China) |
| Abstract: |
| Objective To study the effect and safety of Gabapentin combined with nerve block on the treatment of post-herpetic neuralgia(PHN).Methods Sixty patients with PHN were randomly divided into two groups: nerve block group(group A,n=30) and Gabapentin combined with nerve block group(group B,n=30).The effects were valuated in visual analogue scale(VAS) and according to 24-hour sleeping time，and the side effects and complications were also observed. Results The pain scores after the treatment decreased with time compared with those before treatment in 2 groups during 6 weeks，both the decrease of VAS and the sleeping time within 24 hrs were higher in group B (P＜0.05) . Compared with group A， sleeping time in 24 hour increased in B group (P＜0.05) . Side effects and complications were not found in 2 groups. Conclusions The strategy of oral Gabapentin combined with nerve block is effective and safe for the treatment of PHN，and it is better than nerve block alone. |
| Key words: Gabapentin post-herpetic neuralgia nerve b1ock |
