| 引用本文： |
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吴明,霍惠峰,周家华,等.丙泊酚在无痛上消化道内镜检查术中对血氧饱和度的影响[J].同济大学学报（医学版）,2011,32(1):82-85. [点击复制]
- WU Ming,HUO Hui-feng,ZHOU Jia-hua,et al.Effect of Propofol on heart rate and saturation of blood oxygen during upper gastrointestinal endoscopy examination[J].同济大学学报（医学版）,2011,32(1):82-85. [点击复制]
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| 摘要: |
| 目的 研究上消化道内镜术前使用丙泊酚进行镇静是否会导致氧饱和度下降,并分析导致氧饱和度下降的因素。方法 200例（男103例,女97例）因各种原因进行上消化道内镜检查的患者。采用患者既往及术中实测值。记录术前血氧饱和度、血红蛋白水平和心率。初始氧饱和度＜90%的患者被除外。患者被分为两组。第一组100例接受常规无镇静内镜检查,第二组100例接受镇静内镜检查（镇静剂：丙泊酚1~2 mg/（h·kg-1）。监测患者的血氧饱和度及心率,从口咽部麻醉镇静前开始持续至内镜检查结束后1 min。在内镜检查过程中记录最低的氧饱和度和最大的心率值。记录整个检查过程中氧饱和度〈90%的持续时间,并判断此时内镜检查进行的阶段。结果 两组间的体重指数、吸烟、血红蛋白和最大基础脉率、内镜检查持续时长、最低基氧饱和度、缺氧时间及缺氧持续时间差异无统计学意义。氧饱和度下降情况与性别、内镜检查时长、基础脉搏率及血红蛋白水平无关,而与吸烟有显著关系。结论 丙泊酚作为上消化道系统内镜检查的镇静用药是一种可靠的方法,对没有严重合并症的个体不会产生额外风险。但吸烟习惯应该作为考虑氧饱和度下降的一个影响因素。 |
| 关键词: 内镜 术前用药 丙泊酚 血氧饱和度 吸烟 |
| DOI：10.3969/j.issn1008-0392.2011.01.082 |
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| 基金项目: |
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| Effect of Propofol on heart rate and saturation of blood oxygen during upper gastrointestinal endoscopy examination |
| WU Ming,HUO Hui-feng,ZHOU Jia-hua,CHEN Ying-liang |
| (Dept.of Gastroenterology,Shanghai Seamen's Hospital,Shanghai 200080,China) |
| Abstract: |
| Objective To study the effect of Propofol on the saturation decline of blood oxygen in upper gastrointestinal endoscopy examination and the reason of decline.Methods Two hundred patients(103 men and 97 women) having received upper gastrointestinal endoscopy examination due to various reasons enrolled in this study.Anamnesis and anthropometric values of the patients were taken.Preoperative oxygen saturation,hemoglobin levels and heart rate were recorded.Patients with initial oxygen saturation level＜90% were excluded. Patients were divided into two groups. The first group included 100 patients, who underwent endoscopic examination without sedation and the second group included 100 patients, who underwent endoscopic examination propofol 1~2mg / (kg ? h-1) for sedation. Patients' oxygen saturation and heart rate were monitored from the oropharyngeal anesthesiaheart rate values were recorded. The duration of the oxygen saturation＜90% was recorded throughout the procedure to determine the stage of endoscopy at that time. Results There were no differences between the 2 groups in body mass index, smoking, hemoglobin and basal maximum pulse rate, duration of endoscopy, minimum basal oxygen saturation, duration of hypoxia and time to hypoxia. Reduction of blood oxygen saturation had no relationship with gender, duration of the endoscopy, basal pulse rate and hemoglobin level, but it correlatied with smoking. Conclusions Propofol as a premedication is a reliable method for upper gastrointestinal endoscopy examination and does not produce additional risk of serious complications. However, smoking as a factor of oxygen saturation decrease should be taken into account in patients with upper gastrointestinal endoscopy. |
| Key words: endoscopy premedication Propofol oxygen saturation smoking |
