| 引用本文： |
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王建东,赵春英*,王凤,等.1 192例乳腺癌患者癌因性疲乏的调查及影响因素分析[J].同济大学学报（医学版）,2022,43(3):427-435. [点击复制]
- WANG Jiandong,ZHAO Chunying*,WANG Feng,et al.Survey on prevalence and risk factors of the cancer-related fatigue in 1 192 breast cancer patients[J].同济大学学报（医学版）,2022,43(3):427-435. [点击复制]
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| 摘要: |
| 目的了解乳腺癌患者癌因性疲乏（cancer-related fatigue， CRF）现状，并分析其影响因素。方法采用横断面调查方法，向乳腺癌患者发放调查问卷，按照IDC-10诊断标准判断是否存在CRF，根据Piper疲乏量表中文修订版（Revised Piper Fatigue Scale, RPFS）得分评价疲乏程度，调查乳腺癌患者CRF的发生情况，并分析其影响因素。结果1 192例患者完成了全部调查问卷，乳腺癌患者发生CRF为668例（占56.04%）；以轻、中度疲乏为主，分别占23.95%、55.24%，其中感觉维度得分最高。单因素分析结果显示，文化程度、乳腺癌病程、肿瘤分期、化疗周期、疼痛、上肢水肿、白细胞减少、恶心呕吐、贫血、潮热盗汗、失眠与乳腺癌患者CRF的发生有关（P＜0.05）；多因素Logistic回归分析显示，乳腺癌肿瘤分期、疼痛、白细胞减少、恶心呕吐、潮热盗汗、失眠是CRF发生的危险因素（P＜0.05），病程是其保护因素（P＜0.05）。CRF认知调查显示，乳腺癌患者对CRF认知度低，医护人员对其宣教度低。结论乳腺癌患者发生CRF较为普遍，以轻、中度疲乏为主；乳腺癌肿瘤分期、疼痛、白细胞减少、恶心呕吐、潮热盗汗、失眠是影响患者CRF的危险因素；乳腺癌患者对CRF认知度低。 |
| 关键词: 乳腺癌 癌因性疲乏 影响因素 认知度 |
| DOI：10.12289/j.issn.1008-0392.22062 |
| 投稿时间：2022-03-19 |
| 基金项目: |
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| Survey on prevalence and risk factors of the cancer-related fatigue in 1 192 breast cancer patients |
| WANG Jiandong,ZHAO Chunying*,WANG Feng,ZHENG Jie,LIU Hui* |
| (Department of Breast Surgery, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China) |
| Abstract: |
| ObjectiveTo survey on the prevalence and risk factors of cancer-related fatigue(CRF) in breast cancer patients. MethodsA cross-sectional questionnaire survey was conducted among breast cancer patients from 36 breast cancer follow-up centers nationwide during December 2021 to January 2022. CRF was identified according to the IDC-10 diagnostic criteria, the degree of fatigue was evaluated with the Revised Piper Fatigue Scale（RPFS), and the risk factors of CRF was analyzed with univariate and multivariate Logistic regression. ResultsA total of 1 192 patients completed the questionnaire, CRF was identified in 668（56.04%) patients. The degree of CRF was dominantely mild and moderate（23.95%,55.24%)， and the highest overall score was in sensory dimension. The univariate analysis showed that education level, breast cancer duration, tumor stage, chemotherapy cycle, pain, upper extremity edema, leukopenia, nausea and vomiting, anemia, hectic fever and night sweat, insomnia were associated with CRF in breast cancer patients（P<0.05). Multivariate Logistic regression analysis revealed that breast cancer tumor stage, pain, leukopenia, nausea and vomiting,hectic fever and night sweat, insomnia were risk factors for the CRF（P<0.05)， and the disease duration was a protective factor（P<0.05). The survey revealed that breast cancer patients had low awareness of CRF and lack of advocacy education for patients provided by physicians and nurse. ConclusionCRF is common in patients with breast cancer， usually is mild and moderate. Tumor stage, pain, leukopenia, nausea and vomiting, hectic fever and night sweat, insomnia are risk factors for the CRF; and breast cancer patients have low awareness of CRF. |
| Key words: breast cancer cancer-related fatigue impact factor awareness |
