| 摘要: |
| 本文总结了近10年有关良性前列腺增生（benign prostatic hyperplasia， BPH）流行特征和危险因素的重要文献，发现随着人口老龄化的加剧，世界范围内BPH发病率高且呈上升趋势，而中西方BPH发病率的差距正在缩小。BPH病因很多，其中年龄、性激素、前列腺特异性抗原、生长因子、基因多态性、某些疾病如代谢综合征、肥胖症和慢性前列腺炎等是较为明确的危险因素，而吸烟和饮酒不增加患BPH的风险。 |
| 关键词: 流行病学特征 危险因素 良性前列腺增生 下尿路症状 |
| DOI：10.12289/j.issn.1008-0392.20187 |
| 投稿时间：2020-04-20 |
| 基金项目:国家自然科学基金(81870517)；上海市科学技术委员会科普项目(19DZ2301800) |
|
| Epidemiological characteristics and risk factors of benign prostatic hyperplasia： an update |
| XIE Jin-bo,PENG Bo |
| (Dept. of Urology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai 200072, China) |
| Abstract: |
| The representative literatures on epidemiological characteristics and risk factors of benign prostatic hyperplasia（BPH) in the last 10 years are reviewed. With the increasing aging of population, the incidence of BPH is rising worldwide, as well as in China. Multiple factors are associated with the occurrence of BPH. The age, sex hormone， PSA， cytokines， gene polymorphism， metabolic syndrome， obesity and chronic prostatitis are all incontrovertible risk factors; however, tobacco and alcohol consumption do not increase the risk of BPH. |
| Key words: epidemiological characteristics risk factor benign prostatic hyperplasia lower urinary tract symptoms |
