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  • 张慧,陆媛,马佳,等.GPCOG中文版在社区老年人轻度认知功能障碍筛查中的应用[J].同济大学学报(医学版),2021,42(2):220-225.    [点击复制]
  • ZHANG Hui,LU Yuan,MA Jia,et al.Application of Chinese version of GPCOG in screening of mild cognitive impairment among the elderly in the community[J].同济大学学报(医学版),2021,42(2):220-225.   [点击复制]
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GPCOG中文版在社区老年人轻度认知功能障碍筛查中的应用
张慧,陆媛,马佳,刘文斌,张韶伟,陈慎,任碧金,于德华
0
(同济大学医学院,上海200092; 同济大学医学院附属定海社区卫生服务中心(筹),上海200090;同济大学附属杨浦医院全科医学科,上海200090)
摘要:
目的探讨全科医生认知功能评估量表(GPCOG)中文版在社区老年人群中进行轻度认知功能障碍(mild cognitive impairment, MCI)筛查的应用价值,并寻求GPCOG中文版对轻度认知功能障碍进行筛查的最佳截断值。方法本次研究选取了2019年3月—8月进行体检的65岁以上老年人中通过筛查确诊为MCI的患者110例为病例组,另取同期进行认知筛查且结果为正常的老人112例为对照组。对两组GPCOG评分进行比较分析,并将两组研究对象的GPCOG评分与MMSE及MoCA-B量表评分进行相关性分析。结果对照组的GPCOG 总分和各分项评分均高于病例组,差异具有统计学意义(P<0.05);两组测试对象的GPCOG中文版的评分与MMSE、MoCA-B评分为显著相关(r分别为0.807、0.866,P均<0.01)。GPCOG 总分在对两组进行区分时,其曲线下面积(AUC)为 0.954,灵敏度为86.6%,特异度为89.1%。结论MCI老人的GPCOG中文版评分明显低于正常老人,GPCOG中文版量表可作为社区老年人群MCI初步筛查工具。
关键词:  全科医生认知功能评估量表  轻度认知功能障碍  筛查  老年人
DOI:10.12289/j.issn.1008-0392.20198
投稿时间:2020-04-29
基金项目:上海市卫生健康委员会科研课题面上项目(201940495)
Application of Chinese version of GPCOG in screening of mild cognitive impairment among the elderly in the community
ZHANG Hui,LU Yuan,MA Jia,LIU Wen-bin,ZHANG Shao-wei,CHEN Shen,REN Bi-jin,YU De-hua
(School of Medicine, Tongji University, Shanghai 200092, China; Dinghai Community Health Service Center, School of Medicine, Tongji University, Shanghai 200090, China Dinghai Community Health Service Center, School of Medicine, Tongji University, Shanghai 200090, China;School of Medicine, Tongji University, Shanghai 200092, China; Dept. of General Practice, Yangpu Hospital, School of Medicine, Tongji University, Shanghai 200090, China)
Abstract:
ObjectiveTo evaluate the application of the Chinese version of the general practitioners cognitive function assessment scale(GPCOG-C) screening of mild cognitive impairment(MCI) among elderly population in the community. MethodsOne hundred and ten patients with mild cognitive impairment diagnosed during health check-up in our center from March 2019 to August 2019, and 112 normal elderly subjects in cognitive screening during the same period were enrolled in the study. The GPCOG-C scores of the two groups were compared and the correlation of GPCOG-C scores with mini-mental state examination(MMSE) and Montreal cognitive assessment-basic(MoCA-B) scores were analyzed. ResultsThe total GPCOG-C scores and sub-item scores of the control group were higher than those of the MCI group(P<0.05). The GPCOG-C scores of the two groups were significantly correlated with MMSE and MoCA-B scores(r=0.807 and 0.866, respectively, all P<0.01). The area under ROC curve(AUC) of GPCOG-C total score in diagnosis of MCI was 0.954, taking 12 as GPCOG-C total score cut-off value, the sensitivity was 86.6% and the specificity was 89.1%. ConclusionThe Chinese version GPCOG scores are significantly lower in the elderly with mild cognitive impairment than those in the normal elderly, and the Chinese version of GPCOG scale can be used for MCI screening among elderly population in the community.
Key words:  general practitioners cognitive function assessment scale  mild cognitive impairment  screening  elderly people

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