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陈超波,胡海,蒋兆彦.胆囊切除与脂质代谢异常的研究进展[J].同济大学学报（医学版）,2018,39(1):18-22. [点击复制]
CHEN Chao-bo,HU Hai,JIANG Zhao-yan.Cholecystectomy and lipid metabolism abnormity[J].同济大学学报（医学版）,2018,39(1):18-22. [点击复制]

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胆囊切除与脂质代谢异常的研究进展
陈超波,胡海,蒋兆彦
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(同济大学附属上海市东方医院胆石中心，上海20012;江苏省无锡市锡山人民医院普外科，无锡214011)

摘要:

胆囊结石病与代谢异常相关。胆囊切除术仍是目前胆石病的主要治疗方法，但其对机体特别是脂质代谢如胆汁酸、三酰甘油、胆固醇代谢会产生影响，甚至导致代谢疾病如增加非酒精性脂肪肝（non-alcoholic fatty liver disease, NAFLD）的发生风险。本文对胆囊切除与脂质代谢的关系作一综述。

关键词: 胆囊切除脂质代谢胆囊功能非酒精性脂肪肝

DOI：10.16118/j.1008-0392.2018.01.005

投稿时间：2017-10-19

基金项目:国家自然科学基金（91570577、81570574）；上海市浦东新区卫生系统重点专科建设资助项目（PWZzk2017-10）

Cholecystectomy and lipid metabolism abnormity

CHEN Chao-bo,HU Hai,JIANG Zhao-yan

(Center of Gallbladder Disease, East Hospital, Tongji University, Shanghai 200120, China; Dept. of General Surgery, Xishan Peoples Hospital, Wuxi 214011, Jiangsu Province, China)

Abstract:

Cholelithiasis is a common disease associated with disorders of lipid metabolisms. Cholecystectomy is still a primary therapeutic option for gallstone disease. However, the impact of cholecystectomy on metabolism of bile acids, triglycerides and cholesterol has been drawn great attention, because it may increase the risk of some diseases including non-alcoholic fatty liver disease. We review the recent findings on the relationship between cholecystectomy and disorders of lipid metabolism.

Key words: cholecystectomy lipid metabolism gallbladder function non-alcoholic fatty liver disease