| 摘要: |
| 目的 比较皮秒与纳秒Q开关翠绿宝石激光治疗褐青色痣的疗效及不良反应。方法30例褐青色痣患者随机一侧面部接受皮秒Q开关翠绿宝石激光治疗，另一侧面部接受纳秒Q开关翠绿宝石激光治疗，1次治疗后6个月随访。采用4分法评估疗效，改善>75%为4分，改善51%～75%为3分，改善26%～50%为2分，改善≤25%为1分。观察色素沉着等不良反应。结果30例褐青色痣患者1次治疗6个月后，皮秒Q开关翠绿宝石激光侧疗效评分： 4分1例（3.30%），3分11例(36.70%)，2分9例（30.00%），1分9例（30.00%）；纳秒Q开关翠绿宝石激光侧4分0例，3分1例（3.30%），2分9例（30.00%），1分20例（66.70%）。皮秒Q开关翠绿宝石激光侧色素沉着发生率为43.33%（13/30），低于纳秒Q开关翠绿宝石激光［83.33%(25/30)］（P<0.05）。结论皮秒Q开关翠绿宝石激光疗效显著，色素沉着发生率低，是治疗褐青色痣的理想选择。 |
| 关键词: 皮秒Q开关翠绿宝石激光 纳秒Q开关翠绿宝石激光 褐青色痣 |
| DOI：10.16118/j.1008-0392.2017.05.017 |
| 投稿时间：2017-05-23 |
| 基金项目: |
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| Q-switched alexandrite laser for treatment of Horis nevus： picosecond versus nanosecond |
| YU Yue,CHEN Xiang-dong |
| (Dept. of Dermatology, Ninth Peoples Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China) |
| Abstract: |
| Objective To compare the efficacy and adverse effects of picosecond Q-switched alexandrite laser (PS laser) with nanosecond Q-switched alexandrite laser (NS laser) in treatment of Horis nevus. MethodsThirty patients with Horis nevus received one session of a randomized split-face treatment of PS laser or NS laser. The efficacy was evaluated 6 months after treatment with a quartile rating： >75% improvement (score 4), 51%75% improvement（score 3）, 26%50% improvement(score 2), and ≤25% improvement(score 1). Pigmentation and other adverse effects were observed. ResultsSix month after the treatment for PS laser treatment there were 1 case(3.30%) with score 4, 11 cases(36.70%) with score 3, 9 cases(30.00%) with score 2 and 9 cases(30.00%) with score 1； for NS laser treatment there were none with score 4, 1 case(3.30%) with score 3, 9 cases(30.00%) with score 2 and 20 cases(66.70%) with score 1. The incidence rate of hyperpigmentation was 43.33%(13/30) for PS laser treatment, and 83.33%(25/30) for NS laser treatment. ConclusionPS Laser has better efficacy in treatment of Horis nevus with a lower incidence of hyperpigmentation, suggesting that PS laser may be considered as a better choice for treating Horis nevus. |
| Key words: picosecond Q-switched alexandrite laser nanosecond Q-switched alexandrite laser Hori s nevus |
