| 引用本文： |
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杨东,宋彬,王浩,等.磁共振结肠成像在溃疡性结肠炎严重程度评估中的价值[J].同济大学学报（医学版）,2016,37(3):123-128. [点击复制]
- YANG Dong,SONG Bin,WANG Hao,et al.Value of magnetic resonance colonography for assessment of disease severity in active ulcerative colitis[J].同济大学学报（医学版）,2016,37(3):123-128. [点击复制]
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| 摘要: |
| 目的 探讨磁共振结肠成像(magnetic resonance colonography, MRC)在评估活动性溃疡性结肠炎严重程度中的价值。方法 收集经临床、肠镜及病理证实的活动性溃疡性结肠炎患者23例,根据改良Truelove-Witt's标准将患者分为轻度、中度、重度三组,比较不同组间MRC表现差异。MRC主要评价指标: 黏膜强化、肠壁增厚、肠壁水肿、周围增大淋巴结、梳齿征、深溃疡、病变段DWI高信号。结果 23例活动性溃疡性结肠炎患者中,轻度组4例,中度组8例,重度组11例。肠管周围淋巴结增大在轻度组与重度组间有显著性差异(P=0.009)；肠壁水肿分层和梳齿征在轻度组与重度组间有显著性差异(P=0.001,P=0.004),在中度组与重度间也有显著性差异(P=0.018,P=0.041)；黏膜强化、肠壁增厚及DWI高信号在三组间无显著性差异(P=0.16)；深溃疡仅出现在重度组。结论 磁共振结肠成像(MRC)在评估活动性溃疡性结肠炎严重程度中有一定价值。 |
| 关键词: 磁共振成像 溃疡性结肠炎 弥散加权成像 |
| DOI：10.16118/j.1008-0392.2016.03.025 |
| 投稿时间：2015-09-24 |
| 基金项目:上海市卫计委自然科学基金项目(20134265)；上海市卫生和计划生育委员会基金(20134265) |
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| Value of magnetic resonance colonography for assessment of disease severity in active ulcerative colitis |
| YANG Dong,SONG Bin,WANG Hao,WEI Ran,WANG Pei-jun |
| (Dept.of Imaging and Nuclear Medicine, Medical College, Tongji University, Shanghai 200092, China;Dept.of Radiology, Central Hospital of Minhang District, Shanghai 201199, China;Dept.of Radiology, Tongji Hospital, Tongji University, Shanghai 200065, China) |
| Abstract: |
| Objective To assess magnetic resonance colonography(MRC) in evaluation of disease severity in patients with active ulcerative colitis(UC). Methods Twenty-three patients with active UC confirmed by clinical manifestation, colonoscopy and pathology underwent MRC examination. According to the modified Truelove-Witt's criteria, the patients were classified as mild group(n=4), moderate group(n=8) and severe group(n=11). MRC parameters:mucosa hyperenhancement,wall thickness,mural edema, enlarged mesenteric lymph nodes, comb sign, deep ulcers, diffusion-weighted imaging(DWI) hyperintensity of the lesion segment were evaluated and compared among 3 groups. Results There was significant difference in enlarged mesenteric lymph nodes between mild and severe groups(P=0.009). There were significant differences in mural edema and comb sign between mild and severe groups(P =0.001,P=0.004), and between moderate and severe groups(P=0.018,P=0.041). However, there were no significant differences in mucosa hyperenhancement, bowel wall thickening and DWI hyperintensity of the lesion segment among three groups(P=0.16); the deep ulceration only seen in severe group. Conclusion MRC has a certain value for the assessment of disease severity in patients with active ulcerative colitis. |
| Key words: magnetic resonance imaging ulcerative colitis diffusion weighted imaging |
