| 引用本文： |
-
韩砆石,孙希文.螺旋CT对肺部1cm以下孤立局限性磨玻璃密度结节的诊断价值[J].同济大学学报（医学版）,2015,36(1):78-82, 86. [点击复制]
- HAN Fu-shi,SUN Xi-wen.Diagnostic value of spiral CT for pulmonary small isolated nodules with focal ground-glass opacity[J].同济大学学报（医学版）,2015,36(1):78-82, 86. [点击复制]
|
|
| 摘要: |
| 目的 探讨多排螺旋CT高分辨率扫描对肺部1cm以下孤立局限性磨玻璃密度结节(focal ground-glass opacity, fGGO)的诊断及鉴别诊断。方法 分析经手术病理证实93例肺部1cm以下孤立性fGGO结节的多排螺旋CT征象,其中: 浸润性腺癌15例,微浸润腺癌19例,浸润前病变52例,炎性病变7例。观察病灶形态、大小、边缘、内部结构及临近改变等,评估fGGO结节内实变比例。将观测数据与病理结果进行对照,并采用χ2检验进行统计学分析。结果 1cm以下fGGO结节出现分叶征、毛刺及血管增粗这3种CT征象在浸润性腺癌与浸润前病变之间差异有统计学意义(χ2分别为12.678、6.043、7.147,P值均＜0.05)。随病灶直径增大,fGGO由浸润前病变到浸润性腺癌发生率增加。随着病灶中实变增多,fGGO由浸润前病变到浸润性腺癌发生率增加,小于1cm纯磨玻璃密度结节无浸润性腺癌,而炎性病灶缺少特征性。结论 多层螺旋CT可根据fGGO大小、有无实变,并参照病灶边缘分叶、毛刺以及血管有无增粗,对浸润性腺癌与浸润前病变的诊断及鉴别诊断有一定价值。 |
| 关键词: 肺肿瘤 体层摄影术,X线计算机 不典型腺瘤样增生 |
| DOI：10.16118/j.1008-0392.2015.01.017 |
| 投稿时间：2014-10-14 |
| 基金项目: |
|
| Diagnostic value of spiral CT for pulmonary small isolated nodules with focal ground-glass opacity |
| HAN Fu-shi,SUN Xi-wen |
| (Dept. of Radiology, Pulmonary Hospital, Tongji University, Shanghai 200433, China) |
| Abstract: |
| Objective To investigate the diagnostic and differential diagnostic value of high-resolution multi-slice spiral CT (MSCT) scan for≤1cm isolated nodules with focal ground-glass opacity (fGGO) in the lung. MethodsThe features of 93 pulmonary isolated nodules≤1cm with fGGO on MSCT were retrospectively reviewed. All lesions were pathologically confirmed, including 15 cases of invasive adenocarcinoma, 19 cases of micro-invasive adenocarcinoma, 52 cases of infiltrated precancerous lesions and 7 cases of inflammatory. The morphology, size, edge, and changes in internal and adjacent structure were observed, and the fGGO ratio of nodular consolidation was assessed. The association of MSCT features with pathological findings was analyzed by χ2 test. ResultsThere were significance differences in CT signs of lobulation, glitches and vascular thickening between invasive adenocarcinoma and pre-invasive lesions (χ2=12.678,6.043,7.147, respectively, P＜0.05). The incidence of transition from pre-invasive to invasive adenocarcinoma was increased with the increasing diameter and consolidation of nodules with fGGO; invasive adenocarcinoma was not found in fGGO nodules<1cm in diameter. Meanwhile the inflammatory lesions were lacking of characteristics. ConclusionMulti-slice spiral CT scan can provide valuable information for differential diagnosis of pulmonary isolate nodules≤1cm with focal ground-glass opacity. |
| Key words: lung cancer tomography, X-ray computed atypical adenomatous hyperplasia |
