| 引用本文： |
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莫双阳,常义忠,杨长青.肝硬化患者电解质紊乱的临床分析[J].同济大学学报（医学版）,2013,34(2):58-61. [点击复制]
- MO Shuang-yang,CHANG Yi-zhong,YANG Chang-qing.Electrolytes disorder in patients with cirrhosis[J].同济大学学报（医学版）,2013,34(2):58-61. [点击复制]
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| 摘要: |
| 目的探讨肝硬化患者电解质紊乱情况及其与肝功能Child-pugh分级的关系。方法对162例肝硬化患者肝功能Child-pugh分级、电解质情况及病情预后进行回顾性分析。结果肝硬化患者电解质紊乱以低Na+最为常见,Na+、K+、C1-3种离子均数与肝功能Child-pugh分级有关,尤其是Na+和K+。低Na+、低K+、低C1-发生率随A、B、C分级程度的提高而呈上升趋势(P<0.01)。血Na+水平越低,低K+、肝性脑病、顽固性腹水、死亡的发生率越高,而肝功能Child-pugh分级中的总胆红素、腹腔积液、白蛋白与血Na+水平具有相关性.结论肝硬化患者电解质紊乱以低Na+最为常见,血Na+水平可作为判断肝硬化病情严重程度及预后的重要参考指标。 |
| 关键词: 肝硬化 Child-pugh分级 电解质 低钠血症 预后 |
| DOI：10.3969/j.issn1008-0392.2013.02.014 |
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| 基金项目:国家自然科学基金（81070343）;上海市国际科技合作项目（09410705200） |
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| Electrolytes disorder in patients with cirrhosis |
| MO Shuang-yang,CHANG Yi-zhong,YANG Chang-qing |
| (Dept. of Gastroenterology, Tongji Hospital, Tongji University, Shanghai 200065, China) |
| Abstract: |
| Objective To investigate the relationship between Child-Pugh degree of cirrhosis and electrolytes disorder. Methods The Child-Pugh degree, electrolytes and prognosis were analyzed retrospectively in 162 patients with cirrhosis. Results Low Na+ was mostly common in electrolytes disorder. The mean values of 3 electrolytes were associated with Child-Pugh degree, especially Na+ and K+ The rate of electrolytes disorder was positively correlated with Child-Pugh degree. The Na+ levels were negatively correlated with the incidence rate of low K+ ,hepatic encephalopathy, refractory ascites and death. Multiple regression analysis revealed that the level of Na+ was correlated with total bilirubin, ascites and albumin. Conclusion Low Na+ is mostly common in electrolytes disorder of patients with liver cirrhosis and might be a reliable prognostic marker. |
| Key words: cirrhosis Child-Pugh degree electrolyte hyponatremia prognosis |
