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  • 张琳,汤光宇,李伟,等.多层螺旋CT小肠造影对克罗恩病的诊断价值[J].同济大学学报(医学版),2012,33(5):71-74.    [点击复制]
  • ZHANG Lin,TANG Guang-yu,LI Wei,et al.Application of multislice CT enterography in diagnosis of Crohn’s diease[J].同济大学学报(医学版),2012,33(5):71-74.   [点击复制]
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多层螺旋CT小肠造影对克罗恩病的诊断价值
张琳,汤光宇,李伟,刘勇,陈云燕
0
(同济大学附属第十人民医院放射科)
摘要:
目的探讨多层螺旋CT小肠造影(multi-slice CT enterography,MSCTE)对肠管克罗恩病(Crohn’s diease,CD)的诊断价值。方法对48例临床疑似CD患者进行MSCTE检查,对照肠镜、病理结果,计算其诊断敏感性、特异性,并分析CD的影像学表现,包括发生部位、肠壁增厚程度、强化程度及增强特点、肠腔狭窄程度、并发症及周围脏器受累情况。结果 MSCTE诊断CD的敏感性为89.2%,特异性为36.4%。CD最常见发生部分为末端回肠(81.1%)。影像学表现为:肠壁环形增厚(89.2%),黏膜明显强化(97.3%),黏膜面毛糙,肠壁分层状强化(88.9%),肠腔节段性中-重度狭窄(86.7%)。并发症包括肠梗阻、肠系膜淋巴结增生、梳征(肠系膜血管增粗)、肠瘘。结论 MSCTE是CD的重要影像学检查方法,在CD的诊断、活动性判断及肠外并发症的显示中具有重要意义,结合肠镜、病理结果,有助于提高诊断准确性。
关键词:  克罗恩病  计算机体层摄影术  诊断
DOI:10.3969/j.issn1008 -0392.2012.05.016
投稿时间:2011-09-01
基金项目:
Application of multislice CT enterography in diagnosis of Crohn’s diease
ZHANG Lin,TANG Guang-yu,LI Wei,LIU Yong,CHEN Yun-yan
(Dept.of Radiology,Tenth People’s Hospital,Tongji University,Shanghai 200072,China)
Abstract:
Objective To evaluate the application of multislice CT enterography (MSCTE) in diagnosis of Crohn's diease. Methods MSCTE were performed in 48 patients with suspected Crohn's disease (CD). Using enteroscopy and pathological findings as gold standard, the sensitivity and specificity of MSCTE imaging in diagnosis of Crohn's disease were analyzed. Results The diagnostic sensitivity and specificity of MSCTE were 89. 2% and 36. 4% respectively. The terminal ileum was the most frequently involved in CD (81.1%) . The most common signs of MSCTE were annular thickness of intestinal wall (89. 2%), mucosal hyperenhancement (97.3% ) , mucosal surface coarse, mural stratification enhancement (88. 9% ), moderate to severe segmental luminal narrowing (86. 7%) . The common complications were ileus, mesenteric lymph nodes and the comb sign (prominent vasa recta) and intestinal fistula. Conclusion MSCTE is of value in diagnosis of CD and its complications. MSCTE combined with enteroscopy, pathology and clinical manifestation can improve the diagnosis rate.
Key words:  Crohn's diease  sprial computed tomography  diagnosis

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