| 引用本文： |
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李响,郑雅元,王明敏,等.1990—2009年我国针灸治疗心血管疾病临床研究文献质量的调查[J].同济大学学报（医学版）,2011,32(2):92-98. [点击复制]
- LI Xiang,ZHENG Ya-yuan,WANG Ming-min,et al.Qualities of controlled clinical trials relevant to acupuncture and moxibustion treatment of cardiovascular disease in literatures published in China from 1990——2009[J].同济大学学报（医学版）,2011,32(2):92-98. [点击复制]
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| 摘要: |
| 目的 了解国内近20年来公开发表的与针灸治疗心血管疾病相关的临床研究文献的质量状况,为提高相关研究的质量指明方向。方法 以＂临床治疗＂、＂临床研究＂、＂随机＂、＂对照＂、＂盲法＂、＂针灸＂、＂针刺＂、＂高血压＂、＂冠心病＂、＂心律失常＂为关键词,检索中国生物医学文献数据库、中国学术期刊CNKI数据库、维普中文科技期刊数据库、万方数据库于1990—2009年国内公开发表的与针灸治疗心血管疾病相关的临床研究文献。对文献数量、治疗病种、治疗方法及若干研究质量指标进行综合分析。同时,根据文献中的＂随机＂、＂对照＂、＂盲法＂等研究方法的说明对所有论文进行质量评价。临床试验方法学质量的评估部分参照Jadad评分量表,结合研究中的对照组设置情况进行评分（0~5分）。结果 共纳入分析文献360篇。研究涉及的疾病主要为高血压（38.1%）、冠心病（32.8%）、心律失常（20.6%）。治疗方法以单纯针刺治疗（64.2%）为主。47.2%的研究没有说明其研究是否采用随机化或者其文章说明的随机方法并非真正随机;34.7%的研究提到＂随机＂但未说明其具体的随机方法;18.1%的研究方法符合随机化原则。60%的研究明确设置了对照组。仅3篇文献涉及盲法。根据文献的研究方法说明,得分为0、1、2、3、4、5分的文献分别占36.9%、12.8%、31.9%、18.1%、0.3%、0%。所有文献的平均分为1.32分。结论 1990—2009年国内心血管疾病针灸治疗相关的临床研究文献数量和质量均呈逐年增长趋势,但总体质量仍偏低。 |
| 关键词: 心血管疾病 临床研究 治疗 针灸 质量评价 |
| DOI：10.3969/j.issnl008-0392.2011.02.023 |
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| 基金项目:国家"八六三"高技术研究发展计划（2007AA02Z438）；上海市卫生局青年基金（2008Y051） |
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| Qualities of controlled clinical trials relevant to acupuncture and moxibustion treatment of cardiovascular disease in literatures published in China from 1990——2009 |
| LI Xiang,ZHENG Ya-yuan,WANG Ming-min,LIU Ying,XIAO Jun-jie,CHEN Yi-han |
| (Key Laboratory of Arrhythmias,Ministry of Education of China,Tongji University,Shanghai 200092,China) |
| Abstract: |
| Objective To investigate the qualities of disease published in China in recent 20 years. Methods The clinical research literatures relevant to acupuncture and moxibustion treatment of cardiovascular disease were searched in several databases including the Chinese Biologic Medicine Database disc(CMBdisc),China National Knowledge Infrastructure Database(CNKI),Chongqing VIP full-text Database(VIP),and Wanfang Database.The keywords used were:"clinicalcare","clinical research","randomization","control","blind","acupuncture","hypertension","coronary heart disease"and"arrhythmia"and all references included in the analysis were between 1990 and 2009. The evaluation of clinical trial quality was in accordance with"Jadad Measuring Scale"and"the control group"in the research and was scored from 0 to 5.Results Three hundred and sixty articles with full-text copies online were identified.The common diseases in the above clinical research were hypertension(38.1%),coronary heart disease(32.8%),arrhythmia(20.6%).The treatments(62.4%) adopted were simple acupuncture treatment intervention.The proportion of"no randomization or quasirandomization","randomization without description in details"and"randomization with description of appropriate method"were 47.2%,34.7%,18.1%,respectively.The proportion of articles with"appropriate control group"was 60%.The"blind method"was only found in 3 articles.Score distribution from the worst to the best of the clinical research by quality scale(from 0 to 5) were 0(6.9%),1(12.8%),2(31.9%),3(18.1%),4(0.3%),and 5(0%),respectively,with the mean score of 1.32.Conclusion Though some progress has been made in quantity and quality of articles related to the controlled clinical trials relevant to acupuncture and moxibustion treatment of cardiovascular disease in China during recent years,great challenges still exist in terms of the overall quality. |
| Key words: cardiovascular disease clinical research treatment acupuncture and moxibustion assessment |
