| 摘要: |
| 目的 研究2型糖尿病患者的颈动脉硬化的超声声像图特征。方法 随机选择糖尿病患者98例,另选正常对照50例。所有病例均接受颈动脉常规超声检查、血清生化检查,并计算体质量指数（body mass index,BMI）、胰岛素抵抗指数（HOMA-IR）。比较各组间颈动脉病变情况及实验室检查结果。结果 颈总动脉内膜中层厚度（intimamediathickness,IMT）、Crouse积分、斑块检出率、颈总动脉血流阻力指数（resisitantindex,RI）、胰岛素抵抗指数（HOMA-IR）和超敏C反应蛋白均随着糖尿病病程增加而增加,且差异有统计学意义（P＜0.01）。BMI、HOMA-IR、病程是IMT增厚的独立危险因数。结论 颈动脉超声能很好地反映糖尿病患者动脉硬化的各方面情况,且对制定治疗方案及疗效监测有一定指导作用。 |
| 关键词: 颈动脉超声 糖尿病 内膜中层厚度 |
| DOI：10.3969/j.issnl008-0392.2011.02.016 |
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| 基金项目: |
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| Carotid ultrasonography in diabetes patients |
| ZHANG Yi-feng,CHEN Su-ning |
| (Dept.of Ultrasound,Tongji Hospital,Tongji University,Shanghai 200065,China) |
| Abstract: |
| Objective To study the characteristics of carotid morphology in patients with diabetes. Methods Ninety-eight diabetes patients and 50 normal persons were examined with Doppler ultrasonography for carotid and blood test.Carotid morphology and blood test results of different groups were compared.Results The intima-media thickness(IMT) of common carotid artery (CCA),the Crouse integration,the plaque presence ratio,insulin resistance index(HOMA-IR), c-reaction protein(hs-CRP) and RI of CCA all increased with the course of disease(P＜0.01).The body mass index(BMI),HOMA-IR and disease duration were independent risk factors of IMT(P＜0.05).Conclusions Carotid ultrasonography can well reveal the extent of artery atherosclerosis in diabetes patients and is helpful to form treatment protocols and to monitor the therapeutic effects. |
| Key words: carotid ultrasonography diabetes intima media thickness |
