| 引用本文： |
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张欣文,戴秋萍,董晓超,吴畏,徐思红,陈敖铮.番茄红素对DBP所致果蝇生殖毒性的拮抗作用[J].同济大学学报（医学版）,2007,(5):13-16. [点击复制]
- .Antagonism of lycopene on procreation toxicity in Drosophila melanogaster treated with Di-n-butyl phthalate[J].同济大学学报（医学版）,2007,(5):13-16. [点击复制]
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| 摘要: |
| 目的 研究番茄红素对邻苯二甲酸二丁酯(di-n-butyl phthalate,DBP)所致果蝇生殖毒性的拮抗作用.方法 将果蝇随机分为5组,分别给予溶剂对照培养基和含1.0?P及不同浓度番茄红素的培养基喂饲,雌雄配对产子,每日观察并记录子代孵化数和死亡数.结果 与对照组相比,DBP组果蝇的生育率和平均生育数降低,生育期缩短,子代死亡率升高(P＜0.05);随着番茄红素浓度的增加,染毒果蝇的生育率、生育期和平均生育数逐渐提高,子代死亡率逐渐降低.结论 DBP可对果蝇产生生殖毒性,而番茄红素对这种影响有拮抗作用. |
| 关键词: 番茄红素,邻苯二甲酸二丁酯,生殖毒性,拮抗,果蝇 |
| DOI： |
| 修订日期：2007-05-25 |
| 基金项目:国家自然科学基金资助项目(32371216)，上海市卫生局科研基金资助项目(054092) |
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| Antagonism of lycopene on procreation toxicity in Drosophila melanogaster treated with Di-n-butyl phthalate |
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| Abstract: |
| Objective To study the antagonism of lycopene on procreation toxicity in Drosophila melanogaster treated with di-n-butyl phthalate(DBP).Methods Drosophila melanogasters were randomly divided into five groups and were continuously fed with medium containin |
| Key words: lycopene,di-n-butyl phthalate,procreation toxicity,antagonism,Drosophila melanogaster |
