| 引用本文： |
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齐华林,江薇,马姝琛,马骏,$2,$2.维持性血透患者血浆leptin水平与营养不良的关系[J].同济大学学报（医学版）,2005,(4):45-48. [点击复制]
- .Malnutrition is Associated with Hyperleptinemia in Patients Maintaining Hemodialysis[J].同济大学学报（医学版）,2005,(4):45-48. [点击复制]
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| 摘要: |
| 目的 研究维持性血液透析（MHD）患者血浆leptin水平与营养不良的关系。方法 选择MHD患者25例和健康对照组15例，采用放射免疫法测定血浆leptin水平；用常规营养指标、视黄醇结合蛋白（RBP）、人体测量、生物电阻抗法、改良主观全面营养评价法评价营养状况。结果 MHD患者血浆leptin水平显著高于对照组（P〈0．01）。MHD患者血清前白蛋白（PA）和RBP水平、肱三头肌皮褶厚度（TSF）、瘦体重量指数（LMI）、脂肪重量指数（FMI）均显著低于对照组，血浆leptin、leptin／BMI、leptin／Body Fat Mass、leptin／FMI水平与MS、MAC、TSF、FAT％、FMI呈明显的正相关，其中与FAT％、FMI的相关呈递减趋势；与RBP、LMI呈明显的负相关，其中与LMI相关呈递增趋势。结论 血浆leptin水平可作为评价MHD患者营养状况的指标。 |
| 关键词: 维持性血液透析 高瘦素血症 营养不良 |
| DOI： |
| 修订日期：2005-01-10 |
| 基金项目: |
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| Malnutrition is Associated with Hyperleptinemia in Patients Maintaining Hemodialysis |
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| Abstract: |
| Objective To determine whether plasma leptin level is associated with malnutrition in patients maintaining hemodialysis.Methods Twenty-five MHD patients and fifteen healthy volunteers were included in this study.Plasma leptin levels were measured by RIA.T |
| Key words: hemodialysis hyperleptinaemia protein-energy malnutrition |
