摘要: |
目的 探讨肠缺血再灌流引起肺损伤的细胞机制。方法 成年雄性SD大鼠,随机分为假手术、肠缺血、肠缺血再灌流三组,分别测定各组大鼠肺毛细血管通透性及肺组织髓过氧化酶(是中性粒细胞的特征酶)活性、丙二醛含量、过氧化物歧化酶活性。结果 缺血再灌流组肺髓过氧化酶活性、丙二醛含量及毛细血管通透性均高于缺血组及假手术组。结论 中性粒细胞在大鼠肠缺血再灌流致肺损伤中起了重要作用,介导着肺损伤的发生。 |
关键词: 肠缺血再灌流 肺损伤 中性粒细胞 大鼠 |
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The Role of Polymorphonuclear Neutrophils in Lung Injury Induced by Intestinal Ischemia-reperfusion in Rats |
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Abstract: |
Objective To investigate the relationship bet we en lung injury from intestinal ischemia-reperfusion and polymorphonuclear neutr ophils in rats.Methods 24 adult male SD rats were randomly divided into three groups ( n =8),such as sham-operation,intest |
Key words: intestinal ischemia-reperfusion,lung injury,polymorphonuclear neutrophils,rats |