| 引用本文： |
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赵家胜,贺铭,$2,$2,张秀珍.不同剂量甲硫咪唑治疗Graves病的比较[J].同济大学学报（医学版）,2003,(3):224-226. [点击复制]
- .Methimazole in the Treatment of Graves'''' Disease -Small-Dose Monotherapy or Daily Multiple Large-Dose Therapy?[J].同济大学学报（医学版）,2003,(3):224-226. [点击复制]
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| 摘要: |
| 目的：比较每日一次小剂量与每日多次大剂量甲硫咪唑治疗Graves病的有效性和安全性。方法：患者随机分为2组，单剂量组每日一次口服甲硫咪唑15mg，大剂量组每日一次30mg，分3次口服，然后比较两组的缓解率、药物副反应发生率和停药后的复发率。结果：两组缓解率和复发率相似，但单剂量组的副反发生率显著低于大剂量组。结论：每日15mg单剂量口服甲硫咪唑治疗Graves病疗效与多次大剂量相似，但在安全性方面优于大剂量组。 |
| 关键词: 甲亢 Graves病 甲硫咪唑 剂量 疗效比较 |
| DOI： |
| 修订日期：2003-03-03 |
| 基金项目: |
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| Methimazole in the Treatment of Graves'''' Disease -Small-Dose Monotherapy or Daily Multiple Large-Dose Therapy? |
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| Abstract: |
| Objective To compare the efficacy and safety of small-dose methimazole monotherapy with that of daily large-dose multiple therapy in the treatment of Graves' disease.Methods 50 patients with Graves' disease were divided randomly into two groups: group A |
| Key words: hyperthyroidism,Graves' disease,methimazole,dose |
