| 摘要: |
| 目的：通过对扩张性心肌病、风湿性心脏瓣膜病、陈旧性心肌梗死患者血清中sFas及sFas－L等细胞因子检测，以期了解 DCM发生发展的可能机制。方法：心功能Ⅲ-Ⅳ级DCM患者20例、风湿性心脏瓣膜 病患者24例，OMI患者29例及24例年龄、性别匹配正常对照者。运用EILISA法测sFas及sFas－L，放射免疫法测IL－6、NO、ET、TNF。结果：不同病因所致心衰中，在相同的心功能分级条件下，扩张型心肌病患者sFas、sFas－L明显高于其它病因所致者。结论：心衰患者神经内分泌过度激活，且心肌细胞存在细胞凋亡，DCM发生发展与细胞凋亡密切相关。 |
| 关键词: sFas sFas－L 细胞因子 扩张性心肌病 细胞凋亡 |
| DOI： |
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| 基金项目: |
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| Relations between Soluble Fas Ligard and Other Cytokines with Dilated Cardiomyopathy |
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| Abstract: |
| Objective The purpose of the present study was to examine plasma levels of soluble Fas/Apo-1 receptor (sFas)?soluble Fas ligard (sFas-L) and other cytokines and their relations to dilated cardiomyopathy.Methods Plasma levels of sFas/sFas-L were measured |
| Key words: dilated cardiomyopathy,sFas,sFas-L,apoptosis,cytokine |
