| 摘要: |
| 目的 探讨宁夏枸杞王(lycium barbarum l,LBL）抗石英粉尘的细胞毒作用及其机理。方法 采用体外细胞培养法，用不同浓度LBL处理染石英尘的肺泡巨噬细胞（alveolar macrophage,AM）后，测定肺泡巨噬细胞膜脂质过氧化产物丙二醛（malonadehyde,MDA），AM内超氧化物歧化酶（superoxide dismutse,SOD）活性。结果 LBL能显著抑制AM膜丙二醛（MDA）生成量，以10mg/L LBL作用最显著，且能提高AM内超氧化物歧化酶（SOD）活性。结论 LBL具有抗石英尘对AM脂质过氧化作用。 |
| 关键词: 宁夏枸杞王 石英粉尘 肺泡巨噬细胞 脂质过氧化 抗氧化酶 矽肺 |
| DOI： |
| 修订日期：2002-01-15 |
| 基金项目: |
|
| Effects of Lycium Barbarum L on Lipid Peroxidation and Antioxidant Enzyme of Alveolar Macrophage by Quartz |
|
| () |
| Abstract: |
| Objective To study the effects and mechanism of LBL on the injury of alveolar macrophage exposed to quartz in vitro.Methods Malondialdehyde (MDA) content and superoxide dismutase (SOD) activity of antioxidant enzyme were determined after alveolar macrop |
| Key words: quartz,Lycium Barbarum L(LBL),alveolar macrophage,lipid peroxidation,antioxidant enzyme |
